Was this article helpful?Mass spectrometry (MS) proteomics successfully sequence proteins for the Human Proteome Project (HPP). But quantitative proteomics typically reports random values from irrelevant proteins. Solving reproducible quantitation would...
Was this article helpful?Patient selection for a pharmaceutical clinical trial is a critical process that considers many biomarkers including molecular, clinical and demographic. Since drugs act on protein pathways, molecular...
Was this article helpful?Astrophysics comprises at least two distinct fields requiring different mathematics. Profiling black holes is a modeling exercise, while discovering unknown Saturn moons requires precise raw data mining....
Was this article helpful?Chemical separation requires multiple steps. Using just one single step means low purity, scarce output, or both. Same with digital separation. False discovery rate (FDR), the statistical...
Was this article helpful?Before Copernicus, planetary mathematics was ad hoc and difficult to understand. But his heliocentric abstraction needed only simple math to reveal patterns (circles) that enabled deep insight...
Was this article helpful?To understand today’s proteomics: imagine a Gold Rush started with top earth scientists spending millions to map the landscape and to prospect for treasure, only to find...
Was this article helpful?It’s easy to snorkel in the shallows among tons of colorful fish. But if you want to do marine science, you start with quality scuba gear and...
Was this article helpful?As a tech veteran among academics, I often feel like a chef among nutritional scientists who equate culinary mastery with learning the most recipes. Like cooking, math...
Was this article helpful? View our ASMS 2019 poster HERE for more details on the SorcererSILAC product and technology. Proteomics is a revolution stalled by its reputation as irreproducible pseudo-science....
Was this article helpful?The 2018 Nobel laureate James Allison brings inspiration to all maverick researchers. He bucked convention and toiled at the fringes with custom assays for protein breakthroughs in...